Global Perspectives on Diagnosis and Management of Childhood Epilepsy Disorders

Unmitigated early-life seizures are associated with life-long physical, cognitive, and behavioral impairments. Early and accurate diagnosis of infantile and childhood seizure disorders is a crucial first step in identifying effective treatment that can mitigate the impacts of seizures on the developing brain. Unfortunately, diagnosis and subtype classification of early-onset epilepsies is frequently delayed until long after the seizures have begun. Clinicians need to confidently differentiate Dravet syndrome (DS), Lennox-Gastaut syndrome (LGS), and tuberous sclerosis complex (TSC), as causes of seizure to form efficient strategies to treat these notoriously resistant conditions. Further, the diagnostic journey and disease management of children with epilepsy conditions is associated with significant quality of life (QoL) impacts on both the patient and family.

Please join expert faculty in this live CMEO webcast as they discuss topics including early diagnosis, patient/caregiver QoL, team-based care, the role of pharmaceutical cannabinoid (CBD) in treatment, and regulatory guidelines. Through this discussion learners will become acquainted with improved tactics to diagnose and treat early-life seizures.

Learning Objectives

At the end of this CME/CE activity, participants should be able to:

Utilize validated assessment tools to achieve early and accurate differential diagnosis of rare childhood seizure disorders, including LGS, DS, and TSC.
Incorporate patient/caregiver QoL assessment and treatment goals into team-based management of pediatric seizure disorders.
Examine the role of pharmaceutical CBD in antiepileptic therapy, including outcomes data, formulation/dosing considerations, augmentation strategies, and regulatory requirements.

Financial Support

This program is supported by an independent medical education grant from Jazz Pharmaceuticals, Inc.

Target Audience

Physicians, PAs, nurse practitioners, nurses, pharmacists specializing pediatrics, neurology, primary care practicing in the U.S. and internationally.

Credit Information

Jointly Accredited Provider

In support of improving patient care, CME Outfitters, LLC, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

ABP MOC Credit:
Successful completion of this CME activity, which includes participation in the activity and individual assessment of and feedback to the learner, enables the learner to earn up to 1.0 MOC point in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

Physicians (ACCME):
CME Outfitters, LLC, designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC):
This activity is designated for 1.0 contact hours.

Note to Nurse Practitioners:
Nurse practitioners can apply for AMA PRA Category 1 Credit(s)™ through the American Academy of Nurse Practitioners (AANP). AANP will accept AMA PRA Category 1 Credit(s)™ from Jointly Accredited Organizations. Nurse practitioners can also apply for credit through their state boards.

California Residents:
This continuing nursing education activity was approved by the California Board of Registered Nursing. CME Outfitters LLC’s provider number is CEP15510.

Pharmacists (ACPE):
This application-based activity is approved for 1.0 contact hour (0.10 CEUs) of continuing pharmacy credit (JA0007185-0000-23-027-L01-P).

PAs (AAPA):
CME Outfitters, LLC, has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit. PAs should only claim credit commensurate with the extent of their participation.

ABIM MOC:
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 medical knowledge MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Learning formats:
Live activity

Royal College MOC:
Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

MIPS Improvement Activity:
This activity counts towards MIPS Improvement Activity requirements under the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA). Clinicians should submit their improvement activities by attestation via the CMS Quality Payment Program website.

It is the policy of CME Outfitters, LLC, to ensure independence, balance, objectivity, and scientific rigor and integrity in all of their CE activities. Faculty must disclose to the participants any relationships with commercial companies whose products or devices may be mentioned in faculty presentations, or with the commercial supporter of this CE activity. CME Outfitters, LLC, has evaluated, identified, and mitigated any potential conflicts of interest through a rigorous content validation procedure, use of evidence-based data/research, and a multidisciplinary peer review process. The following information is for participant information only. It is not assumed that these relationships will have a negative impact on the presentations.

Dr. Wirrell reports the following financial relationships:

Advisory Board: Biohaven and Eisai Inc.

Consultant: DSMB for Acadia Pharmaceuticals Inc.; Amicus Therapeutics, Inc.; GRIN Therapeutics; and Neurocrine Biosciences, Inc.

Grants: Dravet Syndrome Foundation

Research Support: (all payments made to Mayo) Marinus Pharmaceuticals, Inc.; UCB, Inc.; and Zogenix, Inc.

The following peer reviewer and CME Outfitters staff have no financial relationships:

Elizabeth Naber, MSN, RN, CCRN-K, CNRN, TCRN (peer reviewer)Evan Luberger (planning committee)Kellie Busby, PharmD (planning committee)Susan H. Yarbrough, CHCP (planning committee)Sandra Caballero, PharmD (planning committee)Sharon Tordoff (planning committee)

Faculty of this CE activity may include discussions of products or devices that are not currently labeled for use by the FDA. The faculty have been informed of their responsibility to disclose to the audience if they will be discussing off-label or investigational uses (any uses not approved by the FDA) of products or devices.

Post-tests, credit request forms, and activity evaluations must be completed online (requires free account activation), and participants can print their certificate or statement of credit immediately (75% pass rate required). This website supports all browsers except Internet Explorer for Mac. For complete technical requirements and privacy policy, visit https://www.cmeoutfitters.com/privacy-and-confidentiality-policy.